I've been running BPs in my system since the beginning of the year to fight a massive HA breakout.
Other than a negative affect on my Blastos and a single Rhodactis shroom, I have nothing but a good experience to report. I have a 50-60 gallon total system and run approximately a single tablespoon of BPs in an IM MiniMax Desktop Reactor...Tank looks the best it's ever looked and I will continue to run them until they prove otherwise. To me, the "trick" with BPs is to use significantly less than they recommend. I started with 1/4 % dosage and have never increased it. I run a SWC 120 cone skimmer and have a very heavy bioload that consists mostly of softies and BTAs, a couple large SPS colonies, a few LPS and 7 fish...
It is set it and forget it...no dosing and no concern of overdosing. I just add a small amount to the reactor every few months as the pellets are consumed...
Fwiw however, I would not consider this a replacement for water changes. I would still maintain a proper regularly scheduled water change regiment...I buddy Joe has one of the best tanks in this community and his WC regiment is undeniably the reason his tank looks so good and healthy.