For me, it comes down to how you can mount/hang the lights and how you aquascape.
Meaning, 2 26 HDs is plenty of power, but if you have a hood that mounts them "close" to the water then you will have hot spots and shadows.
I have a shallow hood, end to end aquascape, and hated the dispersion pattern from 2...so I'm running 4 26HDs @ 40% power to get the light fill I want over my 55g (48"long).
I originally ran 2 52s, but had middle and end shadowing. Then I ran 2 26 and 1 52, but my center overflow wasted a lot of the 52. Not an inexpensive approach, but I sold the 52s and am happy with the 4 26HDs. Note: I have them on rails that allow me to slide them left/right to adjust where "max" light hits.
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2 26HDs is plenty of power...just depends on what you want.