My Fluconazole treatment.

GugsJr

TeamCR
So I had a Bryopsis out break and tried everything from manual removal (don't do this), h202 dip and dosing, lights out and nothing worked.

So I read about Fluconazoleand decided to try it.

I ordered it from Bulk Reef Supply and decided to dose 300 gallons worth on my 220 with about 50gallons worth of water in my sump.

Recommended treatment is 14 days or 21 days for all algae types. Then a 30% water change. I ended up going 21 days.

Well I have to say I'm very pleased.with the treatment.

I lost no corals or fish. I do not have a nem so can't say on that. My zoas, shrooms, sps and feather dusters survived 21 days of the treatment.

The only bad is I had a small cyano patch, small dino outbreak and lost all my macro algae, minus my sea lettuce.

My best guess is the cyano and dinos were already there that the bryopsis was just out competing it.

I've attached a few progress pictures.
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I've tried it also. I had a bad case of Bryopsis and GHA. These are my notes:

I dosed the recommended dose. Turned off the skimmer for 4 days. Kept everything else the same including leaving the chaeto and feather algae in my sump. I left the macro algae in the tank as I read most users didn't see fluconazole affecting them during the first dose and some some limited decline upon a second dose.

Despite most online reports, I found that Bryopsis and GHA do not "melt" away quickly (3-4 days). This could be due to my existing algae load and/or because of over-hyped reporting. At about 1 week, I started to see B & GHA loss, nothing extreme though. Saw more loss at 2 weeks. All of the GHA disappeared with the first treatment. (Strange because all the reports I read said that GHA was much harder to remove.)

At 2.5 weeks, I did a 1/3 water change and then reapplied a second dose of fluconazole. Bryopsis continued to disappear with the second treatment. (I'm sure with the help from fish grazers: pygmy angel, tang, and foxface.)

I would like to confirm that macro algae is affected by a second treatment; they did start to "melt." I removed the dying feather algae and chaeto as they were becoming "soup." (Definitely no need to add more nutrients back into the system.) In aerated fluconazole-free water, I set aside a small sample of macro algae (no visible B or GHA) as a backup source.

Unfortunately, two back-to-back treatments didn't remove all of the Bryopsis. Is it possible that fluconazole only affects new growth? This could explain why the remaining Bryopsis feels course and is next to impossible to remove from the LR.

After two weeks of the second treatment, I did another 1/3 water change. Since I haven't completely removed the Bryopsis, I reintroduced some of my backup macros into the sump. I figure my grazers with keep the remaining B in check for now and the tank rest for now.
 
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