Well,I have been using bio pellets for over a year now ,so I do have some first hand experience in this matter.First of all they do as they advertised.They reduce NO3 and PO4 very effectively.Just like Jeff said ,pellets do their job too well.The key is to start with small amount,about third of recommended dose.You need to monitor your nitrates and phosphates at this stage.About two weeks in,if your NO3 and PO4 still showing, add more pellets.Again monitor your parameters.If they go down to acceptable level do not add more pellets. If still have some PO4 and NO3 add the rest of recommended dose and wait another two weeks.This should do the trick.Doing this slowly like this ,allows your corals to acclimate to changing parameters.If you do it too fast ,you will bleach your corals.Very important is to have very efficient skimmer to remove excess bacteria the reactor produces.Just put the outlet of reactor in front of your skimmer pump inlet.Make sure pellets do not tumble too much in reactor.Need slow flow through the reactor.You might have to start feeding your corals and fish more.I feed 2-3 times daily now,but pellets let me keep demanding SPS corals with healthy amount of fish in my tank.I used to dose vodka ,but it was too much work to dose every day.You could set up a dosing system just like Jeff suggested ,but with pellets is just set it and forget it.A year later I lost about third of pellets,so I will have to replace some soon.Hope this helps.If you have any more questions regarding my set up ,shoot me a PM.You can find my tank on members tank forums,if you want to see how well they work for me.Good Luck.